› 1jss

X-ray diffraction
2.2Å resolution

Crystal structure of the Mus musculus cholesterol-regulated START protein 4 (StarD4).

Released:
DOI: 10.2210/pdb1jss/pdb
PDB entry 1jss coloured by chain, front view.
PDB entry 1jss coloured by chain, side view.
PDB entry 1jss coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Crystal structure of the Mus musculus cholesterol-regulated START protein 4 (StarD4) containing a StAR-related lipid transfer domain.
Romanowski MJ, Soccio RE, Breslow JL, Burley SK
Proc Natl Acad Sci U S A 99 6949-54 (2002)
PMID: 12011453

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189332 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
StAR-related lipid transfer protein 4 Chains: A, B
Molecule details ›
Chains: A, B
Length: 224 amino acids
Theoretical weight: 25.58 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q99JV5 (Residues: 1-224; Coverage: 100%)
Gene name: Stard4
Sequence domains: START domain
Structure domains: Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9A
Spacegroup: P31
Unit cell:
a: 69.966Å b: 69.966Å c: 85.19Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.238 0.238 0.285
Expression system: Escherichia coli BL21

Quick links

Citations

32 review citations

The molecular biology, biochemistry, and physiology of human steroidogenesis and its disorders.
Miller et al. (2011)
31 more

17 mentions without citation

Structural genomics: a pipeline for providing structures for the biologist.
Chance et al. (2002)
16 more