Function and Biology Details
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148888 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Cyclin-dependent kinase 2
Molecule details ›
Chain: A
Length: 298 amino acids
Theoretical weight: 34.06 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Protein kinase domain
Structure domains:
Length: 298 amino acids
Theoretical weight: 34.06 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P24941 (Residues: 1-298; Coverage: 100%)
Sequence domains: Protein kinase domain
Structure domains:
Cyclin-A2
Molecule details ›
Chain: B
Length: 260 amino acids
Theoretical weight: 29.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains: Cyclin-like
Length: 260 amino acids
Theoretical weight: 29.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P20248 (Residues: 173-432; Coverage: 60%)
Sequence domains:
Structure domains: Cyclin-like
Cyclin-dependent kinase inhibitor 1B
Molecule details ›
Chain: C
Length: 84 amino acids
Theoretical weight: 9.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Cyclin-dependent kinase inhibitor
Structure domains: p27
Length: 84 amino acids
Theoretical weight: 9.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P46527 (Residues: 23-106; Coverage: 42%)
Sequence domains: Cyclin-dependent kinase inhibitor
Structure domains: p27
