› 1jux

X-ray diffraction
1.6Å resolution

1.6A Resolution Crystal Structures of the DNA Octamers d(IUATATAC) and d(ITITACAC):Binding of Two Distamycin Drugs Side-by-Side

Released:
DOI: 10.2210/pdb1jux/pdb
PDB entry 1jux coloured by chain, front view.
PDB entry 1jux coloured by chain, side view.
PDB entry 1jux coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Structure of d(ITITACAC) complexed with distamycin at 1.6 A resolution.
Deng J, Pan B, Sundaralingam M
Acta Crystallogr D Biol Crystallogr 59 2342-4 (2003)
PMID: 14646114

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114033 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
5'-D(*IP*TP*IP*TP*AP*CP*AP*C)-3' Chain: A
Molecule details ›
Chain: A
Length: 8 nucleotides
Theoretical weight: 2.4 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand DMY 1 x DMY
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: C2
Unit cell:
a: 33.26Å b: 25.05Å c: 28.3Å
α: 90° β: 124.23° γ: 90°
R-values:
R R work R free
0.149 0.149 0.179
Expression system: Not provided

Quick links

Citations

2 review citations

DNA-binding drugs caught in action: the latest 3D pictures of drug-DNA complexes.
Boer et al. (2009)
1 more

1 mention without citation

DNA conformations and their sequence preferences.
Svozil et al. (2008)