› 1jvm

X-ray diffraction
2.8Å resolution

KCSA POTASSIUM CHANNEL WITH TBA (TETRABUTYLAMMONIUM) AND RUBIDIUM

Released:
DOI: 10.2210/pdb1jvm/pdb
PDB entry 1jvm coloured by chain, front view.
PDB entry 1jvm coloured by chain, side view.
PDB entry 1jvm coloured by chain, top view.
Source organism: Streptomyces lividans
Primary publication:
Energetic optimization of ion conduction rate by the K+ selectivity filter.
Morais-Cabral JH, Zhou Y, MacKinnon R
Nature 414 37-42 (2001)
PMID: 11689935

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assemblies composition:
homo tetramer (preferred)
homo octamer
Assembly name:
PDBe Complex ID:
PDB-CPX-141094 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
pH-gated potassium channel KcsA Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 125 amino acids
Theoretical weight: 13.36 KDa
Source organism: Streptomyces lividans
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A334 (Residues: 1-125; Coverage: 78%)
Gene names: kcsA, skc1
Sequence domains: Ion channel
Structure domains: Helix Hairpins

Ligands and Environments

2 bound ligands:
Ligand RB 3 x RB
Ligand TBA 1 x TBA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID13
Spacegroup: C2
Unit cell:
a: 129.8Å b: 69.4Å c: 112.7Å
α: 90° β: 125.6° γ: 90°
R-values:
R R work R free
0.29 0.281 0.302
Expression system: Escherichia coli

Quick links

Citations

78 review citations

Glutamate receptor ion channels: structure, regulation, and function.
Traynelis et al. (2010)
77 more

11 mentions without citation

Optimization of parameters for semiempirical methods VI: more modifications to the NDDO approximations and re-optimization of parameters.
Stewart JJ. (2013)
10 more