Function and Biology Details
Reaction catalysed:
ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile)
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- Isoleucine-tRNA ligase
- Rossmann-like alpha/beta/alpha sandwich fold
- Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding
- Aminoacyl-tRNA synthetase, class Ia, anticodon-binding
- Isoleucyl tRNA synthetase type 2, anticodon-binding domain
- Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain
- Aminoacyl-tRNA synthetase, class I, conserved site
- Aminoacyl-tRNA synthetase, class Ia
1 more domain
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Isoleucine--tRNA ligase (preferred)
PDBe Complex ID:
PDB-CPX-157524 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Isoleucine--tRNA ligase
Molecule details ›
Chain: A
Length: 821 amino acids
Theoretical weight: 94.68 KDa
Source organism: Thermus thermophilus
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains:
Length: 821 amino acids
Theoretical weight: 94.68 KDa
Source organism: Thermus thermophilus
Expression system: Escherichia coli
UniProt:
- Canonical:
P56690 (Residues: 1-821; Coverage: 79%)
Sequence domains:
Structure domains:
