1jzy

X-ray diffraction
3.5Å resolution

Structural Basis for the Interaction of Antibiotics with the Peptidyl Transferase Center in Eubacteria

Released:
Model geometry
Fit model/data
Data not deposited

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-302832 (preferred)
Entry contents:
3 distinct polypeptide molecules
1 distinct RNA molecule
Macromolecules (4 distinct):
Large ribosomal subunit protein uL4 Chain: K
Molecule details ›
Chain: K
Length: 205 amino acids
Theoretical weight: 22.31 KDa
Source organism: Deinococcus radiodurans
UniProt:
  • Canonical: Q9RXK1 (Residues: 1-205; Coverage: 100%)
Gene names: DR_0312, rplD
Sequence domains: Ribosomal protein L4/L1 family
Large ribosomal subunit protein uL22 Chain: L
Molecule details ›
Chain: L
Length: 134 amino acids
Theoretical weight: 15.19 KDa
Source organism: Deinococcus radiodurans
UniProt:
  • Canonical: Q9RXJ7 (Residues: 1-134; Coverage: 100%)
Gene names: DR_0316, rplV
Sequence domains: Ribosomal protein L22p/L17e
Large ribosomal subunit protein bL32 Chain: M
23S ribosomal RNA Chain: A

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: I222
Unit cell:
a: 169.2Å b: 410Å c: 695Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.273 0.268 0.301