› 1k24

X-ray diffraction
2.03Å resolution

Crystal Structure of the OpcA Outer Membrane Adhesin/Invasin from Neisseria meningitidis

Released:
DOI: 10.2210/pdb1k24/pdb
PDB entry 1k24 coloured by chain, front view.
PDB entry 1k24 coloured by chain, side view.
PDB entry 1k24 coloured by chain, top view.
Source organism: Neisseria meningitidis
Primary publication:
Crystal structure of the OpcA integral membrane adhesin from Neisseria meningitidis.
Prince SM, Achtman M, Derrick JP
Proc Natl Acad Sci U S A 99 3417-21 (2002)
PMID: 11891340

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-175911 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Outer membrane protein Chain: A
Molecule details ›
Chain: A
Length: 253 amino acids
Theoretical weight: 28.09 KDa
Source organism: Neisseria meningitidis
UniProt:
  • Canonical: Q51227 (Residues: 20-272; Coverage: 100%)
Gene names: NMA510612_1388, opc, opcA
Sequence domains: Outer membrane protein OpcA
Structure domains: OPCA outer membrane adhesin/invasin

Ligands and Environments

2 bound ligands:
Ligand ZN 3 x ZN
Ligand 1PE 2 x 1PE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P21212
Unit cell:
a: 96.859Å b: 46.346Å c: 73.977Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.237 0.235 0.274

Quick links

Citations

13 review citations

Molecular basis of bacterial outer membrane permeability revisited.
Nikaido H. (2003)
12 more

21 mentions without citation

The structural biology of β-barrel membrane proteins: a summary of recent reports.
Fairman et al. (2011)
20 more