› 1k8i

X-ray diffraction
3.1Å resolution

CRYSTAL STRUCTURE OF MOUSE H2-DM

Released:
DOI: 10.2210/pdb1k8i/pdb
PDB entry 1k8i coloured by chain, front view.
PDB entry 1k8i coloured by chain, side view.
PDB entry 1k8i coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Crystal structure of mouse H2-M.
Fremont DH, Crawford F, Marrack P, Hendrickson WA, Kappler J
Immunity 9 385-93 (1998)
PMID: 9768758

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151168 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Class II histocompatibility antigen, M alpha chain Chain: A
Molecule details ›
Chain: A
Length: 191 amino acids
Theoretical weight: 21.47 KDa
Source organism: Mus musculus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P28078 (Residues: 30-220; Coverage: 81%)
Gene names: H2-DMa, H2-Ma, Ma
Sequence domains:
Structure domains:
Ig-like domain-containing protein Chain: B
Molecule details ›
Chain: B
Length: 191 amino acids
Theoretical weight: 21.33 KDa
Source organism: Mus musculus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q31099 (Residues: 20-210; Coverage: 79%)
Gene names: H2-DMb2, H2-M beta2, H2-Mb2
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand NAG 2 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: I4
Unit cell:
a: 142.7Å b: 142.7Å c: 76.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.205 0.205 0.256
Expression system: Trichoplusia ni

Quick links

Citations

29 review citations

Pathways of antigen processing.
Blum et al. (2013)
28 more