› 1kcx

X-ray diffraction
2.12Å resolution

X-ray structure of NYSGRC target T-45

Released:
DOI: 10.2210/pdb1kcx/pdb
PDB entry 1kcx coloured by chain, front view.
PDB entry 1kcx coloured by chain, side view.
PDB entry 1kcx coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural bases for CRMP function in plexin-dependent semaphorin3A signaling.
Deo RC, Schmidt EF, Elhabazi A, Togashi H, Burley SK, Strittmatter SM
EMBO J 23 9-22 (2004)
PMID: 14685275

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161301 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dihydropyrimidinase-related protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 518 amino acids
Theoretical weight: 56.37 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P97427 (Residues: 8-525; Coverage: 91%)
Gene names: Crmp1, Dpysl1, Ulip3
Sequence domains: Amidohydrolase family
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9A
Spacegroup: C2221
Unit cell:
a: 123.396Å b: 152.111Å c: 157.165Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.204 0.233
Expression system: Escherichia coli

Quick links

Citations

18 review citations

ALS as a distal axonopathy: molecular mechanisms affecting neuromuscular junction stability in the presymptomatic stages of the disease.
Moloney et al. (2014)
17 more

10 mentions without citation

Structural bases for CRMP function in plexin-dependent semaphorin3A signaling.
Deo et al. (2004)
9 more