› 1kd6

Solution NMR

Solution structure of the eukaryotic pore-forming cytolysin equinatoxin II

Released:
DOI: 10.2210/pdb1kd6/pdb
PDB entry 1kd6 coloured by chain, ensemble of 20 models, front view.
PDB entry 1kd6 coloured by chain, ensemble of 20 models, side view.
PDB entry 1kd6 coloured by chain, ensemble of 20 models, top view.
Source organism: Actinia equina
Primary publication:
Solution structure of the eukaryotic pore-forming cytolysin equinatoxin II: implications for pore formation.
Hinds MG, Zhang W, Anderluh G, Hansen PE, Norton RS
J Mol Biol 315 1219-29 (2002)
PMID: 11827489

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158432 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DELTA-actitoxin-Aeq1a Chain: A
Molecule details ›
Chain: A
Length: 179 amino acids
Theoretical weight: 19.86 KDa
Source organism: Actinia equina
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P61914 (Residues: 36-214; Coverage: 92%)
Sequence domains: Sea anemone cytotoxic protein
Structure domains: Cytolysin/lectin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dyanamics distance geometry simulated annealing
Expression system: Escherichia coli BL21(DE3)

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Citations

16 review citations

Pore-forming toxins: ancient, but never really out of fashion.
Dal Peraro et al. (2016)
15 more

4 mentions without citation

Sea Anemone Toxins: A Structural Overview.
Madio et al. (2019)
3 more