Function and Biology Details
Reaction catalysed:
Succinate + a quinone = fumarate + a quinol
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Fumarate reductase, subunit D
- Fumarate reductase, subunit C
- Fumarate reductase/succinate dehydrogenase, transmembrane subunit
- 4Fe-4S ferredoxin-type, iron-sulphur binding domain
- 2Fe-2S ferredoxin-type iron-sulfur binding domain
- Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily
- FAD/NAD(P)-binding domain superfamily
- 4Fe-4S ferredoxin, iron-sulphur binding, conserved site
13 more domains
Structure domains:
- Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD)
- Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
- Fumarate reductase/Succinate dehydogenase iron-sulfur protein, C-terminal domain
- 2Fe-2S ferredoxin domains from multidomain proteins
- Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
- Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
Structure analysis Details
Assemblies composition:
Assembly name:
Fumarate reductase (preferred)
PDBe Complex ID:
PDB-CPX-132439 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Fumarate reductase flavoprotein subunit
Molecule details ›
Chains: A, M
Length: 602 amino acids
Theoretical weight: 66.06 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains:
Length: 602 amino acids
Theoretical weight: 66.06 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical:
P00363 (Residues: 1-602; Coverage: 100%)
Sequence domains:
Structure domains:
Fumarate reductase iron-sulfur subunit
Molecule details ›
Chains: B, N
Length: 243 amino acids
Theoretical weight: 27.02 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains:
Length: 243 amino acids
Theoretical weight: 27.02 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical: P0AC47 (Residues: 2-244; Coverage: 100%)
Sequence domains:
Structure domains:
Fumarate reductase subunit C
Molecule details ›
Chains: C, O
Length: 130 amino acids
Theoretical weight: 14.9 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains: Fumarate reductase subunit C
Structure domains: Fumarate reductase/succinate dehydrogenase, transmembrane subunit
Length: 130 amino acids
Theoretical weight: 14.9 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical: P0A8Q0 (Residues: 2-131; Coverage: 99%)
Sequence domains: Fumarate reductase subunit C
Structure domains: Fumarate reductase/succinate dehydrogenase, transmembrane subunit
Fumarate reductase subunit D
Molecule details ›
Chains: D, P
Length: 119 amino acids
Theoretical weight: 13.12 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains: Fumarate reductase subunit D
Structure domains: Fumarate reductase/succinate dehydrogenase, transmembrane subunit
Length: 119 amino acids
Theoretical weight: 13.12 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical: P0A8Q3 (Residues: 1-119; Coverage: 100%)
Sequence domains: Fumarate reductase subunit D
Structure domains: Fumarate reductase/succinate dehydrogenase, transmembrane subunit
