› 1kfp

Solution NMR

Solution structure of the antimicrobial 18-residue gomesin

Released:
DOI: 10.2210/pdb1kfp/pdb
PDB entry 1kfp coloured by chain, ensemble of 20 models, front view.
PDB entry 1kfp coloured by chain, ensemble of 20 models, side view.
PDB entry 1kfp coloured by chain, ensemble of 20 models, top view.
Source organism: Acanthoscurria gomesiana
Primary publication:
The solution structure of gomesin, an antimicrobial cysteine-rich peptide from the spider.
Mandard N, Bulet P, Caille A, Daffre S, Vovelle F
Eur. J. Biochem. 269 1190-8 (2002)
PMID: 11856345

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160625 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gomesin Chain: A
Molecule details ›
Chain: A
Length: 19 amino acids
Theoretical weight: 2.28 KDa
Source organism: Acanthoscurria gomesiana
Expression system: Not provided
UniProt:
  • Canonical: P82358 (Residues: 24-41; Coverage: 30%)

Ligands and Environments

No bound ligands
1 modified residue:
Ligand PCA 1 x PCA

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry simulated annealing energy minimization
Expression system: Not provided

Quick links

Citations

12 review citations

Anti-microbial peptides: from invertebrates to vertebrates.
Bulet et al. (2004)
11 more

9 mentions without citation

Resistance is futile: targeting multidrug-resistant bacteria with de novo Cys-rich cyclic polypeptides.
Mourenza et al. (2023)
8 more