› 1kjv

X-ray diffraction
1.48Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-139412 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Ig-like domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 284 amino acids
Theoretical weight: 33.02 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q95565 (Residues: 1-276; Coverage: 80%)
Gene name: RT1.A1(C)
Sequence domains:
Structure domains:
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 100 amino acids
Theoretical weight: 11.78 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P07151 (Residues: 21-119; Coverage: 100%)
Gene name: B2m
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Ubiquilin-1 Chain: P
Molecule details ›
Chain: P
Length: 9 amino acids
Theoretical weight: 1.01 KDa
Source organism: Rattus norvegicus
Expression system: Not provided
UniProt:
  • Canonical: Q9JJP9 (Residues: 450-458; Coverage: 2%)
Gene names: Da41, Plic1, Ubqln1

Ligands and Environments

1 bound ligand:
Ligand SO4 4 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 48.397Å b: 50.522Å c: 200.073Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.164 0.162 0.191
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

2 review citations

TAP genes and immunity.
McCluskey et al. (2004)
1 more

4 mentions without citation

The Structure of a Peptide-Loaded Shark MHC Class I Molecule Reveals Features of the Binding between β2-Microglobulin and H Chain Conserved in Evolution.
Wu et al. (2021)
3 more