› 1kke

X-ray diffraction
2.6Å resolution

Crystal Structure of Reovirus Attachment Protein Sigma1 Trimer

Released:
DOI: 10.2210/pdb1kke/pdb
PDB entry 1kke coloured by chain, front view.
PDB entry 1kke coloured by chain, side view.
PDB entry 1kke coloured by chain, top view.
Source organism: Mammalian orthoreovirus 3 Dearing
Primary publication:
Crystal structure of reovirus attachment protein sigma1 reveals evolutionary relationship to adenovirus fiber.
Chappell JD, Prota AE, Dermody TS, Stehle T
EMBO J 21 1-11 (2002)
PMID: 11782420

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137113 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Outer capsid protein sigma-1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 210 amino acids
Theoretical weight: 22.69 KDa
Source organism: Mammalian orthoreovirus 3 Dearing
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P03528 (Residues: 246-455; Coverage: 46%)
Gene name: S1
Sequence domains: Reovirus viral attachment protein sigma 1
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P212121
Unit cell:
a: 52.7Å b: 89Å c: 119.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.172 0.172 0.232
Expression system: Spodoptera frugiperda

Quick links

Citations

42 review citations

Adenoviruses as vaccine vectors.
Tatsis et al. (2004)
41 more

12 mentions without citation

Homotrimeric, beta-stranded viral adhesins and tail proteins.
Weigele et al. (2003)
11 more