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Solution NMR

NMR STRUCTURAL ANALYSIS OF THE COMPLEX FORMED BETWEEN ALPHA-BUNGAROTOXIN AND THE PRINCIPAL ALPHA-NEUROTOXIN BINDING SEQUENCE ON THE ALPHA7 SUBUNIT OF A NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-149797 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Alpha-bungarotoxin Chain: A
Molecule details ›
Chain: A
Length: 74 amino acids
Theoretical weight: 8.01 KDa
Source organism: Bungarus multicinctus
UniProt:
  • Canonical: P60615 (Residues: 22-95; Coverage: 100%)
Structure domains: CD59
Neuronal acetylcholine receptor subunit alpha-7 Chain: B
Molecule details ›
Chain: B
Length: 20 amino acids
Theoretical weight: 2.35 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli
UniProt:
  • Canonical: P22770 (Residues: 201-219; Coverage: 4%)
Gene name: CHRNA7

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY DYNAMIC SIMULATED ANNEALING
Expression system: Escherichia coli