› 1kql

X-ray diffraction
2.7Å resolution

Crystal structure of the C-terminal region of striated muscle alpha-tropomyosin at 2.7 angstrom resolution

Released:
DOI: 10.2210/pdb1kql/pdb
PDB entry 1kql coloured by chain, front view.
PDB entry 1kql coloured by chain, side view.
PDB entry 1kql coloured by chain, top view.
Source organisms:
Primary publication:
The crystal structure of the C-terminal fragment of striated-muscle alpha-tropomyosin reveals a key troponin T recognition site.
Li Y, Mui S, Brown JH, Strand J, Reshetnikova L, Tobacman LS, Cohen C
Proc Natl Acad Sci U S A 99 7378-83 (2002)
PMID: 12032291

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-136501 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
General control transcription factor GCN4; Tropomyosin alpha-1 chain Chains: A, B
Molecule details ›
Chains: A, B
Length: 56 amino acids
Theoretical weight: 6.6 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
  • Canonical: P03069 (Residues: 255-278; Coverage: 9%)
  • Canonical: P04692 (Residues: 254-284; Coverage: 11%)
Gene names: AAS101, AAS3, ARG9, Alpha-tm, GCN4, Tpm1, Tpma, YEL009C
Sequence domains: Basic region leucine zipper
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P6422
Unit cell:
a: 137.202Å b: 137.202Å c: 40.071Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.255 0.252 0.289
Expression system: Escherichia coli

Quick links

Citations

10 review citations

Calcium, thin filaments, and the integrative biology of cardiac contractility.
Kobayashi et al. (2005)
9 more

10 mentions without citation

Two crystal structures of Trichoderma reesei hydrophobin HFBI--the structure of a protein amphiphile with and without detergent interaction.
Hakanpää et al. (2006)
9 more