› 1ks6

Solution NMR

Transforming Growth Factor Beta type II receptor ligand binding domain

Released:
DOI: 10.2210/pdb1ks6/pdb
PDB entry 1ks6 coloured by chain, ensemble of 20 models, front view.
PDB entry 1ks6 coloured by chain, ensemble of 20 models, side view.
PDB entry 1ks6 coloured by chain, ensemble of 20 models, top view.
Source organism: Gallus gallus
Primary publication:
Solution structure of the chick TGFbeta type II receptor ligand-binding domain.
Marlow MS, Brown CB, Barnett JV, Krezel AM
J Mol Biol 326 989-97 (2003)
PMID: 12589747

Function and Biology Details

Reaction catalysed: 
ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187455 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TGF-beta receptor type-2 Chain: A
Molecule details ›
Chain: A
Length: 107 amino acids
Theoretical weight: 12.07 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q90999 (Residues: 36-142; Coverage: 20%)
Gene name: TGFBR2
Sequence domains: Transforming growth factor beta receptor 2 ectodomain
Structure domains: CD59

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Mechanisms of TGF-beta signaling from cell membrane to the nucleus.
Shi et al. (2003)
2 more

1 mention without citation

Solution structure and phylogenetics of Prod1, a member of the three-finger protein superfamily implicated in salamander limb regeneration.
Garza-Garcia et al. (2009)