› 1l5b

X-ray diffraction
2Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160490 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cyanovirin-N Chains: A, B
Molecule details ›
Chains: A, B
Length: 101 amino acids
Theoretical weight: 11.02 KDa
Source organism: Nostoc ellipsosporum
Expression system: Escherichia coli
UniProt:
  • Canonical: P81180 (Residues: 1-101; Coverage: 100%)
Sequence domains: CVNH domain
Structure domains: Cyanovirin-N

Ligands and Environments

2 bound ligands:
Ligand NA 1 x NA
Ligand NHE 1 x NHE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9B
Spacegroup: P41212
Unit cell:
a: 61.966Å b: 61.966Å c: 148.4Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.247 0.247 0.258
Expression system: Escherichia coli

Quick links

Citations

16 review citations

The unfolding story of three-dimensional domain swapping.
Rousseau et al. (2003)
15 more

11 mentions without citation

An update of the recombinant protein expression systems of Cyanovirin-N and challenges of preclinical development.
Lotfi et al. (2018)
10 more