› 1l6n

Solution NMR

STRUCTURE OF THE N-TERMINAL 283-RESIDUE FRAGMENT OF THE HIV-1 GAG POLYPROTEIN

Released:
DOI: 10.2210/pdb1l6n/pdb
PDB entry 1l6n coloured by chain, ensemble of 20 models, front view.
PDB entry 1l6n coloured by chain, ensemble of 20 models, side view.
PDB entry 1l6n coloured by chain, ensemble of 20 models, top view.
Source organism: Human immunodeficiency virus 1
Primary publication:
Structure of the N-terminal 283-residue fragment of the immature HIV-1 Gag polyprotein.
Tang C, Ndassa Y, Summers MF
Nat Struct Biol 9 537-43 (2002)
PMID: 12032547

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180773 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gag Polyprotein Chain: A
Molecule details ›
Chain: A
Length: 289 amino acids
Theoretical weight: 32.39 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q72497 (Residues: 1-283; Coverage: 57%)
Gene name: gag
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing, torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)

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Citations

18 review citations

HIV-1 assembly, budding, and maturation.
Sundquist et al. (2012)
17 more

7 mentions without citation

Viral precursor polyproteins: keys of regulation from replication to maturation.
Yost et al. (2013)
6 more