› 1l7c

X-ray diffraction
2.5Å resolution

alpha-catenin fragment, residues 385-651

Released:
DOI: 10.2210/pdb1l7c/pdb
PDB entry 1l7c coloured by chain, front view.
PDB entry 1l7c coloured by chain, side view.
PDB entry 1l7c coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Biochemical and structural definition of the l-afadin- and actin-binding sites of alpha-catenin.
Pokutta S, Drees F, Takai Y, Nelson WJ, Weis WI
J Biol Chem 277 18868-74 (2002)
PMID: 11907041

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-150675 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Catenin alpha-1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 269 amino acids
Theoretical weight: 30.21 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P26231 (Residues: 385-651; Coverage: 30%)
Gene names: Catna1, Ctnna1
Sequence domains: Vinculin family
Structure domains: Alpha-catenin/vinculin-like

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 18 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL1-5
Spacegroup: P212121
Unit cell:
a: 64.78Å b: 105.29Å c: 123.91Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.238 0.238 0.273
Expression system: Escherichia coli BL21

Quick links

Citations

51 review citations

Sticky business: orchestrating cellular signals at adherens junctions.
Perez-Moreno et al. (2003)
50 more

10 mentions without citation

Biochemical and structural definition of the l-afadin- and actin-binding sites of alpha-catenin.
Pokutta et al. (2002)
9 more