› 1la4

Solution NMR

Solution Structure of SGTx1

Released:
DOI: 10.2210/pdb1la4/pdb
PDB entry 1la4 coloured by chain, ensemble of 20 models, front view.
PDB entry 1la4 coloured by chain, ensemble of 20 models, side view.
PDB entry 1la4 coloured by chain, ensemble of 20 models, top view.
Source organism: Stromatopelma calceatum griseipes
Primary publication:
Solution structure and functional characterization of SGTx1, a modifier of Kv2.1 channel gating.
Lee CW, Kim S, Roh SH, Endoh H, Kodera Y, Maeda T, Kohno T, Wang JM, Swartz KJ, Kim JI
Biochemistry 43 890-7 (2004)
PMID: 14744131

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157570 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kappa-theraphotoxin-Scg1a Chain: A
Molecule details ›
Chain: A
Length: 34 amino acids
Theoretical weight: 3.79 KDa
Source organism: Stromatopelma calceatum griseipes
Expression system: Not provided
UniProt:
  • Canonical: P56855 (Residues: 1-34; Coverage: 100%)
Sequence domains: Ion channel inhibitory toxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry, simulated annealing
Expression system: Not provided

Quick links

Citations

14 review citations

The hitchhiker's guide to the voltage-gated sodium channel galaxy.
Ahern et al. (2016)
13 more

15 mentions without citation

Tarantula toxins interacting with voltage sensors in potassium channels.
Swartz KJ. (2007)
14 more