› 1lbq

X-ray diffraction
2.4Å resolution

The crystal structure of Saccharomyces cerevisiae ferrochelatase

Released:
DOI: 10.2210/pdb1lbq/pdb
PDB entry 1lbq coloured by chain, front view.
PDB entry 1lbq coloured by chain, side view.
PDB entry 1lbq coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Metal binding to Saccharomyces cerevisiae ferrochelatase.
Karlberg T, Lecerof D, Gora M, Silvegren G, Labbe-Bois R, Hansson M, Al-Karadaghi S
Biochemistry 41 13499-506 (2002)
PMID: 12427010

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147781 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ferrochelatase, mitochondrial Chains: A, B
Molecule details ›
Chains: A, B
Length: 362 amino acids
Theoretical weight: 41 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P16622 (Residues: 32-393; Coverage: 92%)
Gene names: HEM15, YOR176W
Sequence domains: Ferrochelatase
Structure domains: Rossmann fold

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I711
Spacegroup: P212121
Unit cell:
a: 86.61Å b: 97.169Å c: 121.574Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.255 0.255 0.282
Expression system: Escherichia coli

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Citations

4 review citations

Structure and function of enzymes in heme biosynthesis.
Layer et al. (2010)
3 more

7 mentions without citation

Making and breaking heme.
Celis et al. (2019)
6 more