Function and Biology Details
Reactions catalysed:
ATP + a protein = ADP + a phosphoprotein
ATP + L-seryl/L-threonyl/L-tyrosyl-[protein] = ADP + O-phospho-L-seryl/O-phospho-L-threonyl/O-phospho-L-tyrosyl-[protein]
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126711 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Mitogen-activated protein kinase 14
Molecule details ›
Chain: A
Length: 360 amino acids
Theoretical weight: 41.34 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Protein kinase domain
Structure domains:
Length: 360 amino acids
Theoretical weight: 41.34 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P47811 (Residues: 1-360; Coverage: 100%)
Sequence domains: Protein kinase domain
Structure domains:
Dual specificity mitogen-activated protein kinase kinase 3
Molecule details ›
Chain: B
Length: 18 amino acids
Theoretical weight: 2.07 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
Length: 18 amino acids
Theoretical weight: 2.07 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
- Canonical: O09110 (Residues: 15-32; Coverage: 5%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 19-ID
Spacegroup:
P3121
Expression systems:
- Escherichia coli BL21(DE3)
- Not provided
