› 1lie

X-ray diffraction
1.6Å resolution

X-RAY CRYSTALLOGRAPHIC STRUCTURES OF ADIPOCYTE LIPID BINDING PROTEIN COMPLEXED WITH PALMITATE AND HEXADECANESULFONIC ACID. PROPERTIES OF CAVITY BINDING SITES

Released:
DOI: 10.2210/pdb1lie/pdb
PDB entry 1lie coloured by chain, front view.
PDB entry 1lie coloured by chain, side view.
PDB entry 1lie coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
X-ray crystallographic structures of adipocyte lipid-binding protein complexed with palmitate and hexadecanesulfonic acid. Properties of cavity binding sites.
LaLonde JM, Bernlohr DA, Banaszak LJ
Biochemistry 33 4885-95 (1994)
PMID: 8161548

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137406 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fatty acid-binding protein, adipocyte Chain: A
Molecule details ›
Chain: A
Length: 131 amino acids
Theoretical weight: 14.59 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: P04117 (Residues: 2-132; Coverage: 99%)
Gene names: Ap2, Fabp4
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

2 bound ligands:
Ligand PLM 1 x PLM
Ligand PPI 1 x PPI
1 modified residue:
Ligand OCS 1 x OCS

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2
Unit cell:
a: 119.54Å b: 37.86Å c: 28.57Å
α: 90° β: 92.66° γ: 90°
R-values:
R R work R free
0.198 0.198 0.239
Expression system: Not provided

Quick links

Citations

8 review citations

Binding of small-molecule ligands to proteins: "what you see" is not always "what you get".
Mobley et al. (2009)
7 more

5 mentions without citation

Recognition of functional sites in protein structures.
Shulman-Peleg et al. (2004)
4 more