› 1ljy

X-ray diffraction
2.9Å resolution

Crystal Structure of a Novel Regulatory 40 kDa Mammary Gland Protein (MGP-40) secreted during Involution

Released:
DOI: 10.2210/pdb1ljy/pdb
PDB entry 1ljy coloured by chain, front view.
PDB entry 1ljy coloured by chain, side view.
PDB entry 1ljy coloured by chain, top view.
Source organism: Capra hircus
Primary publication:
Crystal structure of a novel regulatory 40-kDa mammary gland protein (MGP-40) secreted during involution.
Mohanty AK, Singh G, Paramasivam M, Saravanan K, Jabeen T, Sharma S, Yadav S, Kaur P, Kumar P, Srinivasan A, Singh TP
J Biol Chem 278 14451-60 (2003)
PMID: 12529329

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186082 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Chitinase-3-like protein 1 Chain: A
Molecule details ›
Chain: A
Length: 361 amino acids
Theoretical weight: 40.59 KDa
Source organism: Capra hircus
UniProt:
  • Canonical: Q8SPQ0 (Residues: 22-383; Coverage: 100%)
Gene name: CHI3L1
Sequence domains: Glycosyl hydrolases family 18
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, NDG
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 62.95Å b: 65.89Å c: 107.03Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.181 0.234

Quick links

Citations

10 review citations

Plasma YKL-40: a potential new cancer biomarker?
Johansen et al. (2009)
9 more

2 mentions without citation

Sequence and structural analysis of the chitinase insertion domain reveals two conserved motifs involved in chitin-binding.
Li et al. (2010)
1 more