› 1lmi

X-ray diffraction
1.5Å resolution

1.5 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF A SECRETED PROTEIN FROM MYCOBACTERIUM TUBERCULOSIS-MPT63

Released:
DOI: 10.2210/pdb1lmi/pdb
PDB entry 1lmi coloured by chain, front view.
PDB entry 1lmi coloured by chain, side view.
PDB entry 1lmi coloured by chain, top view.
Source organism: Mycobacterium tuberculosis
Primary publication:
Crystal structure of a major secreted protein of Mycobacterium tuberculosis-MPT63 at 1.5-A resolution.
Goulding CW, Parseghian A, Sawaya MR, Cascio D, Apostol MI, Gennaro ML, Eisenberg D
Protein Sci 11 2887-93 (2002)
PMID: 12441386

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161651 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Immunogenic protein MPT63 Chain: A
Molecule details ›
Chain: A
Length: 131 amino acids
Theoretical weight: 13.75 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: P9WIP1 (Residues: 30-159; Coverage: 100%)
Gene names: MTCY09F9.38, Rv1926c, mpt63
Sequence domains: Domain of unknown function (DUF1942)
Structure domains: Immunoglobulin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X8C
Spacegroup: P6522
Unit cell:
a: 43.129Å b: 43.129Å c: 228.798Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.198 0.197 0.252
Expression system: Escherichia coli K-12

Quick links

Citations

6 review citations

Molecular paleontology and complexity in the last eukaryotic common ancestor.
Koumandou et al. (2013)
5 more

3 mentions without citation

The bright and dark sides of protein conformational switches and the unifying forces of infections.
Sannigrahi et al. (2020)
2 more