› 1lpv

Solution NMR

DROSOPHILA MELANOGASTER DOUBLESEX (DSX), NMR, 18 STRUCTURES

Released:
DOI: 10.2210/pdb1lpv/pdb
PDB entry 1lpv coloured by chain, ensemble of 18 models, front view.
PDB entry 1lpv coloured by chain, ensemble of 18 models, side view.
PDB entry 1lpv coloured by chain, ensemble of 18 models, top view.
Source organism: Drosophila melanogaster
Primary publication:
Sexual dimorphism in diverse metazoans is regulated by a novel class of intertwined zinc fingers.
Zhu L, Wilken J, Phillips NB, Narendra U, Chan G, Stratton SM, Kent SB, Weiss MA
Genes Dev 14 1750-64 (2000)
PMID: 10898790

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149865 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein doublesex Chain: A
Molecule details ›
Chain: A
Length: 52 amino acids
Theoretical weight: 6.13 KDa
Source organism: Drosophila melanogaster
Expression system: Not provided
UniProt:
  • Canonical: P23023 (Residues: 35-86; Coverage: 10%)
Gene names: CG11094, dsx
Sequence domains: DM DNA binding domain
Structure domains: DM DNA-binding domain

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY AND SIMULATED ANNEALING
Expression system: Not provided

Quick links

Citations

16 review citations

Zinc finger proteins: new insights into structural and functional diversity.
Laity et al. (2001)
15 more

4 mentions without citation

Nonsynonymous mutations within APOB in human familial hypobetalipoproteinemia: evidence for feedback inhibition of lipogenesis and postendoplasmic reticulum degradation of apolipoprotein B.
Zhong et al. (2010)
3 more