› 1lqh

Solution NMR

INSECTICIDAL ALPHA SCORPION TOXIN ISOLATED FROM THE VENOM OF SCORPION LEIURUS QUINQUESTRIATUS HEBRAEUS, NMR, MINIMIZED AVERAGE STRUCTURE

Released:
DOI: 10.2210/pdb1lqh/pdb
PDB entry 1lqh coloured by chain, front view.
PDB entry 1lqh coloured by chain, side view.
PDB entry 1lqh coloured by chain, top view.
Source organism: Leiurus quinquestriatus hebraeus
Primary publication:
Solution structures of a highly insecticidal recombinant scorpion alpha-toxin and a mutant with increased activity.
Tugarinov V, Kustanovich I, Zilberberg N, Gurevitz M, Anglister J
Biochemistry 36 2414-24 (1997)
PMID: 9054546

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148149 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-insect toxin LqhaIT Chain: A
Molecule details ›
Chain: A
Length: 65 amino acids
Theoretical weight: 7.4 KDa
Source organism: Leiurus quinquestriatus hebraeus
Expression system: Escherichia coli
UniProt:
  • Canonical: P17728 (Residues: 20-82; Coverage: 96%)
Sequence domains: Scorpion toxin-like domain
Structure domains: Knottin, scorpion toxin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Escherichia coli

Quick links

Citations

10 review citations

Scorpion toxins specific for Na+-channels.
Possani et al. (1999)
9 more

5 mentions without citation

Systematic comparison of crystal and NMR protein structures deposited in the protein data bank.
Sikic et al. (2010)
4 more