› 1lri

X-ray diffraction
1.45Å resolution

BETA-CRYPTOGEIN-CHOLESTEROL COMPLEX

Released:
DOI: 10.2210/pdb1lri/pdb
PDB entry 1lri coloured by chain, front view.
PDB entry 1lri coloured by chain, side view.
PDB entry 1lri coloured by chain, top view.
Source organism: Phytophthora cryptogea
Primary publication:
The 1.45 A resolution structure of the cryptogein-cholesterol complex: a close-up view of a sterol carrier protein (SCP) active site.
Lascombe MB, Ponchet M, Venard P, Milat ML, Blein JP, Prangé T
Acta Crystallogr D Biol Crystallogr 58 1442-7 (2002)
PMID: 12198300

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147408 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-elicitin cryptogein Chain: A
Molecule details ›
Chain: A
Length: 98 amino acids
Theoretical weight: 10.33 KDa
Source organism: Phytophthora cryptogea
UniProt:
  • Canonical: P15570 (Residues: 21-118; Coverage: 100%)
Sequence domains: Elicitin
Structure domains: Elicitin domain

Ligands and Environments

2 bound ligands:
Ligand CL 1 x CL
Ligand CLR 1 x CLR
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LURE BEAMLINE DW32
Spacegroup: C2221
Unit cell:
a: 30.964Å b: 94.8Å c: 65.296Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.13 0.127 0.188

Quick links

Citations

24 citation in other articles

Structure of a cholesterol-binding protein deficient in Niemann-Pick type C2 disease.
Friedland et al. (2003)
23 more

9 mentions without citation

Cholesterol as a co-solvent and a ligand for membrane proteins.
Song et al. (2014)
8 more