› 1lwr

Solution NMR

Solution structure of the NCAM fibronectin type III module 2

Released:
DOI: 10.2210/pdb1lwr/pdb
PDB entry 1lwr coloured by chain, ensemble of 30 models, front view.
PDB entry 1lwr coloured by chain, ensemble of 30 models, side view.
PDB entry 1lwr coloured by chain, ensemble of 30 models, top view.
Source organism: Rattus norvegicus
Primary publication:
Structural basis for a direct interaction between FGFR1 and NCAM and evidence for a regulatory role of ATP.
Kiselyov VV, Skladchikova G, Hinsby AM, Jensen PH, Kulahin N, Soroka V, Pedersen N, Tsetlin V, Poulsen FM, Berezin V, Bock E
Structure 11 691-701 (2003)
PMID: 12791257

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146668 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neural cell adhesion molecule 1 Chain: A
Molecule details ›
Chain: A
Length: 96 amino acids
Theoretical weight: 10.66 KDa
Source organism: Rattus norvegicus
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P13596 (Residues: 612-705; Coverage: 11%)
Gene names: Ncam, Ncam1
Sequence domains: Fibronectin type III domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry; simulated annealing
Expression system: Komagataella pastoris

Quick links

Citations

37 review citations

Cell adhesion and signalling by cadherins and Ig-CAMs in cancer.
Cavallaro et al. (2004)
36 more

3 mentions without citation

Mechanism of homophilic adhesion by the neural cell adhesion molecule: use of multiple domains and flexibility.
Johnson et al. (2004)
2 more