Function and Biology Details
Reaction catalysed:
ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148282 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Bone morphogenetic protein 7
Molecule details ›
Chain: A
Length: 139 amino acids
Theoretical weight: 15.7 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines
Length: 139 amino acids
Theoretical weight: 15.7 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
- Canonical:
P18075 (Residues: 293-431; Coverage: 35%)
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines
Activin receptor type-2A
Molecule details ›
Chain: B
Length: 102 amino acids
Theoretical weight: 12.02 KDa
Source organism: Mus musculus
Expression system: Komagataella pastoris
UniProt:
Sequence domains: Activin types I and II receptor domain
Structure domains: CD59
Length: 102 amino acids
Theoretical weight: 12.02 KDa
Source organism: Mus musculus
Expression system: Komagataella pastoris
UniProt:
- Canonical: P27038 (Residues: 20-121; Coverage: 21%)
Sequence domains: Activin types I and II receptor domain
Structure domains: CD59
Ligands and Environments
Experiments and Validation Details
X-ray source:
SSRL BEAMLINE BL11-1
Spacegroup:
P6222
Expression systems:
- Cricetulus griseus
- Komagataella pastoris
