› 1lyn

X-ray diffraction
2.75Å resolution

CRYSTAL STRUCTURE AND SUBUNIT DYNAMICS OF THE LYSIN DIMER: EGG ENVELOPES DISSOCIATE DIMERS, THE MONOMER IS THE ACTIVE SPECIES

Released:
DOI: 10.2210/pdb1lyn/pdb
PDB entry 1lyn coloured by chain, front view.
PDB entry 1lyn coloured by chain, side view.
PDB entry 1lyn coloured by chain, top view.
Source organism: Haliotis rufescens
Primary publication:
Crystal structure and subunit dynamics of the abalone sperm lysin dimer: egg envelopes dissociate dimers, the monomer is the active species.
Shaw A, Fortes PA, Stout CD, Vacquier VD
J Cell Biol 130 1117-25 (1995)
PMID: 7657696

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137911 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Egg-lysin Chains: A, B
Molecule details ›
Chains: A, B
Length: 136 amino acids
Theoretical weight: 16.3 KDa
Source organism: Haliotis rufescens
Expression system: Not provided
UniProt:
  • Canonical: P04552 (Residues: 19-154; Coverage: 100%)
Sequence domains: Egg lysin (Sperm-lysin)
Structure domains: Fertilization protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P2221
Unit cell:
a: 51.2Å b: 47Å c: 123.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.233 0.233 not available
Expression system: Not provided

Quick links

Citations

4 review citations

Selection in the rapid evolution of gamete recognition proteins in marine invertebrates.
Vacquier et al. (2011)
3 more

1 mention without citation

Structural Basis of Egg Coat-Sperm Recognition at Fertilization.
Raj et al. (2017)