› 1m38

X-ray diffraction
1.8Å resolution

Structure of Inorganic Pyrophosphatase

Released:
DOI: 10.2210/pdb1m38/pdb
PDB entry 1m38 coloured by chain, front view.
PDB entry 1m38 coloured by chain, side view.
PDB entry 1m38 coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Three-dimensional structure of Saccharomyces cerevisiae inorganic pyrophosphatase complexed with cobalt and phosphate ions
Kuranova IP, Polyakov KM, Smirnova EA, Hohne WE, Lamzin VS, Meijers R
Crystallography Reports 48 953-958 (2003)

Function and Biology Details

Reaction catalysed: 
Diphosphate + H(2)O = 2 phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133603 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Inorganic pyrophosphatase Chains: A, B
Molecule details ›
Chains: A, B
Length: 287 amino acids
Theoretical weight: 32.34 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P00817 (Residues: 1-287; Coverage: 100%)
Gene names: IPP1, PPA, PPA1, YBR011C, YBR0202
Sequence domains: Inorganic pyrophosphatase
Structure domains: Inorganic pyrophosphatase

Ligands and Environments

2 bound ligands:
Ligand CO 6 x CO
Ligand PO4 2 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P21
Unit cell:
a: 51.69Å b: 93.23Å c: 69.84Å
α: 90° β: 99.74° γ: 90°
R-values:
R R work R free
0.193 0.193 0.241

Quick links

Citations

3 mentions without citation

Sudden Cardiac Death Due to Deficiency of the Mitochondrial Inorganic Pyrophosphatase PPA2.
Kennedy et al. (2016)
2 more