› 1m3c

Solution NMR

Solution structure of a circular form of the N-terminal SH3 domain (E132C, E133G, R191G mutant) from oncogene protein c-Crk

Released:
DOI: 10.2210/pdb1m3c/pdb
PDB entry 1m3c coloured by chain, ensemble of 20 models, front view.
PDB entry 1m3c coloured by chain, ensemble of 20 models, side view.
PDB entry 1m3c coloured by chain, ensemble of 20 models, top view.
Source organism: Mus musculus
Primary publication:
Changing protein backbone topology: Structural and dynamic consequences of the backbone cyclization in SH3 domain
Schumann FH, Varadan R, Tayakuniyil PP, Hall JB, Camarero JA, Fushman D
To be published

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179108 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adapter molecule crk Chain: A
Molecule details ›
Chain: A
Length: 60 amino acids
Theoretical weight: 7.03 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q64010 (Residues: 132-191; Coverage: 20%)
Gene names: Crk, Crko
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: Simulated annealing combined with torsion angle dynamics
Expression system: Escherichia coli

Quick links