› 1m6c

X-ray diffraction
1.9Å resolution

V68N MYOGLOBIN WITH CO

Released:
DOI: 10.2210/pdb1m6c/pdb
PDB entry 1m6c coloured by chain, front view.
PDB entry 1m6c coloured by chain, side view.
PDB entry 1m6c coloured by chain, top view.
Source organism: Sus scrofa
Primary publication:
Stabilizing bound O2 in myoglobin by valine68 (E11) to asparagine substitution.
Krzywda S, Murshudov GN, Brzozowski AM, Jaskolski M, Scott EE, Klizas SA, Gibson QH, Olson JS, Wilkinson AJ
Biochemistry 37 15896-907 (1998)
PMID: 9843395

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-135413 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myoglobin Chains: A, B
Molecule details ›
Chains: A, B
Length: 153 amino acids
Theoretical weight: 17 KDa
Source organism: Sus scrofa
Expression system: Escherichia coli
UniProt:
  • Canonical: P02189 (Residues: 2-154; Coverage: 99%)
Gene name: MB
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

2 bound ligands:
Ligand HEM 2 x HEM
Ligand CMO 2 x CMO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Unit cell:
a: 122.14Å b: 42.3Å c: 91.55Å
α: 90° β: 92.49° γ: 90°
R-values:
R R work R free
0.192 0.192 0.261
Expression system: Escherichia coli

Quick links

Citations

14 citation in other articles

Hydration of protein-protein interfaces.
Rodier et al. (2005)
13 more

2 mentions without citation

Effects of local protein environment on the binding of diatomic molecules to heme in myoglobins. DFT and dispersion-corrected DFT studies.
Liao et al. (2013)
1 more