› 1mcp

X-ray diffraction
2.7Å resolution

PHOSPHOCHOLINE BINDING IMMUNOGLOBULIN FAB MC/PC603. AN X-RAY DIFFRACTION STUDY AT 2.7 ANGSTROMS

Released:
DOI: 10.2210/pdb1mcp/pdb
PDB entry 1mcp coloured by chain, front view.
PDB entry 1mcp coloured by chain, side view.
PDB entry 1mcp coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Phosphocholine binding immunoglobulin Fab McPC603. An X-ray diffraction study at 2.7 A.
Satow Y, Cohen GH, Padlan EA, Davies DR
J Mol Biol 190 593-604 (1986)
PMID: 3097327

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-224973 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
IGA-KAPPA MCPC603 FAB (LIGHT CHAIN) Chain: L
Molecule details ›
Chain: L
Length: 220 amino acids
Theoretical weight: 24.11 KDa
Source organism: Mus musculus
Expression system: Not provided
Structure domains: Immunoglobulins
Ig heavy chain V region M603 Chain: H
Molecule details ›
Chain: H
Length: 222 amino acids
Theoretical weight: 24.32 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: P01789 (Residues: 1-122; Coverage: 100%)
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P63
Unit cell:
a: 162.531Å b: 162.531Å c: 60.719Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.225 0.225 not available
Expression system: Not provided

Quick links

Citations

45 review citations

Conformations of immunoglobulin hypervariable regions.
Chothia et al. (1989)
44 more

20 mentions without citation

Impact of the Protein Data Bank on antineoplastic approvals.
Westbrook et al. (2020)
19 more