› 1mkm

X-ray diffraction
2.2Å resolution

CRYSTAL STRUCTURE OF THE THERMOTOGA MARITIMA ICLR

Released:
DOI: 10.2210/pdb1mkm/pdb
PDB entry 1mkm coloured by chain, front view.
PDB entry 1mkm coloured by chain, side view.
PDB entry 1mkm coloured by chain, top view.
Source organism: Thermotoga maritima
Primary publication:
Crystal structure of Thermotoga maritima 0065, a member of the IclR transcriptional factor family.
Zhang RG, Kim Y, Skarina T, Beasley S, Laskowski R, Arrowsmith C, Edwards A, Joachimiak A, Savchenko A
J Biol Chem 277 19183-90 (2002)
PMID: 11877432

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194433 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcriptional regulator, IclR family Chains: A, B
Molecule details ›
Chains: A, B
Length: 249 amino acids
Theoretical weight: 28.45 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9WXS0 (Residues: 1-246; Coverage: 100%)
Gene name: TM_0065
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand ZN 2 x ZN
Ligand FMT 1 x FMT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2
Unit cell:
a: 115.229Å b: 61.076Å c: 95.911Å
α: 90° β: 110.51° γ: 90°
R-values:
R R work R free
0.257 0.232 0.3
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Bacterial transcriptional regulators for degradation pathways of aromatic compounds.
Tropel et al. (2004)
3 more

8 mentions without citation

Towards fully automated structure-based function prediction in structural genomics: a case study.
Watson et al. (2007)
7 more