› 1myn

Solution NMR

SOLUTION STRUCTURE OF DROSOMYCIN, THE FIRST INDUCIBLE ANTIFUNGAL PROTEIN FROM INSECTS, NMR, 15 STRUCTURES

Released:
DOI: 10.2210/pdb1myn/pdb
PDB entry 1myn coloured by chain, ensemble of 15 models, front view.
PDB entry 1myn coloured by chain, ensemble of 15 models, side view.
PDB entry 1myn coloured by chain, ensemble of 15 models, top view.
Source organism: Drosophila melanogaster
Primary publication:
Solution structure of drosomycin, the first inducible antifungal protein from insects.
Landon C, Sodano P, Hetru C, Hoffmann J, Ptak M
Protein Sci 6 1878-84 (1997)
PMID: 9300487

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154470 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Drosomycin Chain: A
Molecule details ›
Chain: A
Length: 44 amino acids
Theoretical weight: 4.91 KDa
Source organism: Drosophila melanogaster
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P41964 (Residues: 27-70; Coverage: 88%)
Gene names: CG10810, CRP, Drs
Sequence domains: Gamma-thionin family
Structure domains: Knottin, scorpion toxin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY, RESTRAINED SIMULATED ANNEALING AND ENERGY MINIMIZATION
Expression system: Saccharomyces cerevisiae

Quick links

Citations

20 review citations

Mode of action of membrane active antimicrobial peptides.
Shai Y. (2002)
19 more

10 mentions without citation

Insect antimicrobial peptides and their applications.
Yi et al. (2014)
9 more