› 1mz9

X-ray diffraction
1.7Å resolution

Storage function of COMP:the crystal structure of the coiled-coil domain in complex with vitamin D3

Released:
DOI: 10.2210/pdb1mz9/pdb
PDB entry 1mz9 coloured by chain, front view.
PDB entry 1mz9 coloured by chain, side view.
PDB entry 1mz9 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Storage function of cartilage oligomeric matrix protein: the crystal structure of the coiled-coil domain in complex with vitamin D(3).
Ozbek S, Engel J, Stetefeld J
EMBO J 21 5960-8 (2002)
PMID: 12426368

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193082 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cartilage oligomeric matrix protein Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 45 amino acids
Theoretical weight: 5.24 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9R0G6 (Residues: 28-71; Coverage: 6%)
Gene name: Comp
Sequence domains: Cartilage oligomeric matrix protein
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces

Ligands and Environments

1 bound ligand:
Ligand VDY 2 x VDY
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7B
Spacegroup: P21
Unit cell:
a: 38.295Å b: 49.289Å c: 55.26Å
α: 90° β: 103.87° γ: 90°
R-values:
R R work R free
0.231 0.231 0.254
Expression system: Escherichia coli

Quick links

Citations

11 review citations

Coiled coil domains: stability, specificity, and biological implications.
Mason et al. (2004)
10 more

8 mentions without citation

Protein Design: From the Aspect of Water Solubility and Stability.
Qing et al. (2022)
7 more