› 1n0y

X-ray diffraction
1.75Å resolution

Crystal Structure of Pb-bound Calmodulin

Released:
DOI: 10.2210/pdb1n0y/pdb
PDB entry 1n0y coloured by chain, front view.
PDB entry 1n0y coloured by chain, side view.
PDB entry 1n0y coloured by chain, top view.
Source organism: Paramecium tetraurelia
Primary publication:
Domain flexibility in the 1.75 A resolution structure of Pb2+-calmodulin.
Wilson MA, Brunger AT
Acta Crystallogr D Biol Crystallogr 59 1782-92 (2003)
PMID: 14501118

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139596 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calmodulin Chains: A, B
Molecule details ›
Chains: A, B
Length: 148 amino acids
Theoretical weight: 16.69 KDa
Source organism: Paramecium tetraurelia
Expression system: Escherichia coli
UniProt:
  • Canonical: P07463 (Residues: 2-149; Coverage: 99%)
Gene names: CAM, GSPATT00015825001
Sequence domains: EF-hand domain pair
Structure domains: EF-hand

Ligands and Environments

3 bound ligands:
Ligand PB 14 x PB
Ligand CAC 1 x CAC
Ligand ACT 1 x ACT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-1
Spacegroup: C2
Unit cell:
a: 100.936Å b: 30.792Å c: 113.084Å
α: 90° β: 109.31° γ: 90°
R-values:
R R work R free
0.214 0.213 0.223
Expression system: Escherichia coli

Quick links

Citations

2 review citations

X-ray Scattering Studies of Protein Structural Dynamics.
Meisburger et al. (2017)
1 more

6 mentions without citation

Defining potential roles of Pb(2+) in neurotoxicity from a calciomics approach.
Gorkhali et al. (2016)
5 more