› 1n2w

Solution NMR

Solution Structure of 8OG:G mismatch containing duplex

Released:
DOI: 10.2210/pdb1n2w/pdb
PDB entry 1n2w coloured by chain, front view.
PDB entry 1n2w coloured by chain, side view.
PDB entry 1n2w coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Solution structure of a DNA duplex containing 8-hydroxy-2'-deoxyguanosine opposite deoxyguanosine.
Thiviyanathan V, Somasunderam A, Hazra TK, Mitra S, Gorenstein DG
J Mol Biol 325 433-42 (2003)
PMID: 12498794

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114221 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(8OG)P*GP*CP*G)-3' Chains: A, B
Molecule details ›
Chains: A, B
Length: 12 nucleotides
Theoretical weight: 3.72 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand 8OG 2 x 8OG

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 47%
Refinement method: Relaxation matrix refinement, molecular dynamics, simulated annealing
Expression system: Not provided

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Citations

2 review citations

Chemistry and structural biology of DNA damage and biological consequences.
Stone et al. (2011)
1 more