› 1n8c

Solution NMR

Solution Structure of a Cis-Opened (10R)-N6-Deoxyadenosine Adduct of (9S,10R)-(9,10)-Epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in a DNA Duplex

Released:
DOI: 10.2210/pdb1n8c/pdb
PDB entry 1n8c coloured by chain, ensemble of 11 models, front view.
PDB entry 1n8c coloured by chain, ensemble of 11 models, side view.
PDB entry 1n8c coloured by chain, ensemble of 11 models, top view.
Source organism: Synthetic construct
Primary publication:
Solution structure of a cis-opened (10R)-N6-deoxyadenosine adduct of (9S,10R)-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in a DNA duplex.
Volk DE, Thiviyanathan V, Rice JS, Luxon BA, Shah JH, Yagi H, Sayer JM, Yeh HJ, Jerina DM, Gorenstein DG
Biochemistry 42 1410-20 (2003)
PMID: 12578353

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114237 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
5'-D(*CP*GP*GP*TP*CP*AP*CP*GP*AP*GP*G)-3' Chain: A
Molecule details ›
Chain: A
Length: 11 nucleotides
Theoretical weight: 3.4 KDa
Source organism: Synthetic construct
Expression system: Not provided
5'-D(*CP*CP*TP*CP*GP*TP*GP*AP*CP*CP*G)-3' Chain: B
Molecule details ›
Chain: B
Length: 11 nucleotides
Theoretical weight: 3.31 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand TBC 1 x TBC
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

6 review citations

Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stability.
Sharma et al. (2006)
5 more

1 mention without citation

Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase.
Ling et al. (2004)