› 1n8m

Solution NMR

Solution structure of Pi4, a four disulfide bridged scorpion toxin active on potassium channels

Released:
DOI: 10.2210/pdb1n8m/pdb
PDB entry 1n8m coloured by chain, ensemble of 10 models, front view.
PDB entry 1n8m coloured by chain, ensemble of 10 models, side view.
PDB entry 1n8m coloured by chain, ensemble of 10 models, top view.
Source organism: Pandinus imperator
Primary publication:
Solution structure of Pi4, a short four-disulfide-bridged scorpion toxin specific of potassium channels.
Guijarro JI, M'Barek S, Gómez-Lagunas F, Garnier D, Rochat H, Sabatier JM, Possani L, Delepierre M, Possani L
Protein Sci 12 1844-54 (2003)
PMID: 12930984

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157696 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Potassium channel toxin alpha-KTx 6.4 Chain: A
Molecule details ›
Chain: A
Length: 38 amino acids
Theoretical weight: 4.2 KDa
Source organism: Pandinus imperator
Expression system: Not provided
UniProt:
  • Canonical: P58498 (Residues: 1-38; Coverage: 100%)
Sequence domains: Scorpion short toxin, BmKK2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

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Citations

1 review citation

Current views on scorpion toxins specific for K+-channels.
Rodríguez de la Vega et al. (2004)
6 other articles

1 mention without citation

Solution structure of Pi4, a short four-disulfide-bridged scorpion toxin specific of potassium channels.
Guijarro et al. (2003)