› 1na8

X-ray diffraction
2.3Å resolution

Crystal structure of ADP-ribosylation factor binding protein GGA1

Released:
DOI: 10.2210/pdb1na8/pdb
PDB entry 1na8 coloured by chain, front view.
PDB entry 1na8 coloured by chain, side view.
PDB entry 1na8 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Binding partners for the COOH-terminal appendage domains of the GGAs and gamma-adaptin.
Lui WW, Collins BM, Hirst J, Motley A, Millar C, Schu P, Owen DJ, Robinson MS
Mol Biol Cell 14 2385-98 (2003)
PMID: 12808037

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193829 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ADP-ribosylation factor-binding protein GGA1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 154 amino acids
Theoretical weight: 17.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UJY5 (Residues: 494-639; Coverage: 23%)
Gene name: GGA1
Sequence domains: Adaptin C-terminal domain
Structure domains: Immunoglobulin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P3221
Unit cell:
a: 65.426Å b: 65.426Å c: 142.725Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.219 0.216 0.279
Expression system: Escherichia coli

Quick links

Citations

12 review citations

Adaptable adaptors for coated vesicles.
Robinson MS. (2004)
11 more

2 mentions without citation

Protein subunit interfaces: heterodimers versus homodimers.
Zhanhua et al. (2005)
1 more