› 1nem

Solution NMR

Saccharide-RNA recognition in the neomycin B / RNA aptamer complex

Released:
DOI: 10.2210/pdb1nem/pdb
PDB entry 1nem coloured by chain, ensemble of 9 models, front view.
PDB entry 1nem coloured by chain, ensemble of 9 models, side view.
PDB entry 1nem coloured by chain, ensemble of 9 models, top view.
Source organism: Synthetic construct
Primary publication:
Saccharide-RNA recognition in a complex formed between neomycin B and an RNA aptamer.
Jiang L, Majumdar A, Hu W, Jaishree TJ, Xu W, Patel DJ
Structure 7 817-27 (1999)
PMID: 10425683

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196139 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecules (2 distinct):
5'-R(*GP*GP*AP*CP*UP*GP*GP*GP*CP*GP*AP*GP*AP*AP*GP*UP*UP*UP*AP*GP*UP*CP*C)-3' Chain: A
Molecule details ›
Chain: A
Length: 23 nucleotides
Theoretical weight: 7.46 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

Carbohydrate polymer : NEW Components: BDR, IDG
Carbohydrate polymer
2 bound ligands:
Ligand BDG 1 x BDG
Ligand NEB 1 x NEB
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE RESTRAINED MOLECULAR DYNAMICS
Expression system: Not provided

Quick links

Citations

8 review citations

Aminoglycoside-RNA interactions.
Walter et al. (1999)
7 more

13 mentions without citation

Selection and Biosensor Application of Aptamers for Small Molecules.
Pfeiffer et al. (2016)
12 more