› 1no8

Solution NMR

SOLUTION STRUCTURE OF THE NUCLEAR FACTOR ALY RBD DOMAIN

Released:
DOI: 10.2210/pdb1no8/pdb
PDB entry 1no8 coloured by chain, ensemble of 32 models, front view.
PDB entry 1no8 coloured by chain, ensemble of 32 models, side view.
PDB entry 1no8 coloured by chain, ensemble of 32 models, top view.
Source organism: Mus musculus
Primary publication:
Structure of the nuclear factor ALY: insights into post-transcriptional regulatory and mRNA nuclear export processes.
Pérez-Alvarado GC, Martínez-Yamout M, Allen MM, Grosschedl R, Dyson HJ, Wright PE
Biochemistry 42 7348-57 (2003)
PMID: 12809490

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126639 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
THO complex subunit 4 Chain: A
Molecule details ›
Chain: A
Length: 106 amino acids
Theoretical weight: 11.51 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O08583 (Residues: 77-182; Coverage: 42%)
Gene names: Aly, Alyref, Ref1, Refbp1, THOC4
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing torsion angle dynamics molecular dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

The RNA recognition motif, a plastic RNA-binding platform to regulate post-transcriptional gene expression.
Maris et al. (2005)
1 more

4 mentions without citation

Characterization of epitranscriptome reader proteins experimentally and in silico: Current knowledge and future perspectives beyond the YTH domain.
Miller et al. (2023)
3 more