› 1nq3

X-ray diffraction
2.2Å resolution

Crystal structure of the mammalian tumor associated antigen UK114

Released:
DOI: 10.2210/pdb1nq3/pdb
PDB entry 1nq3 coloured by chain, front view.
PDB entry 1nq3 coloured by chain, side view.
PDB entry 1nq3 coloured by chain, top view.
Source organism: Capra hircus
Primary publication:
Structure and oligomeric state of the mammalian tumour-associated antigen UK114.
Deriu D, Briand C, Mistiniene E, Naktinis V, Grütter MG
Acta Crystallogr D Biol Crystallogr 59 1676-8 (2003)
PMID: 12925811

Function and Biology Details

Reaction catalysed: 
2-iminobutanoate + H(2)O = 2-oxobutanoate + NH(3)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160434 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
2-iminobutanoate/2-iminopropanoate deaminase Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 136 amino acids
Theoretical weight: 14.18 KDa
Source organism: Capra hircus
Expression system: Escherichia coli
UniProt:
  • Canonical: P80601 (Residues: 2-137; Coverage: 99%)
Gene name: RIDA
Sequence domains: Endoribonuclease L-PSP
Structure domains: RutC-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P212121
Unit cell:
a: 51.035Å b: 77.998Å c: 192.51Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.188 0.188 0.226
Expression system: Escherichia coli

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Citations

3 review citations

Understanding microbial metabolism.
Downs DM. (2006)
2 more

7 mentions without citation

RidA Proteins Protect against Metabolic Damage by Reactive Intermediates.
Irons et al. (2020)
6 more