› 1nyo

Solution NMR

Solution structure of the antigenic TB protein MPT70/MPB70

Released:
DOI: 10.2210/pdb1nyo/pdb
PDB entry 1nyo coloured by chain, ensemble of 38 models, front view.
PDB entry 1nyo coloured by chain, ensemble of 38 models, side view.
PDB entry 1nyo coloured by chain, ensemble of 38 models, top view.
Source organism: Mycobacterium tuberculosis
Primary publication:
Solution structure of the Mycobacterium tuberculosis complex protein MPB70: from tuberculosis pathogenesis to inherited human corneal desease.
Carr MD, Bloemink MJ, Dentten E, Whelan AO, Gordon SV, Kelly G, Frenkiel TA, Hewinson RG, Williamson RA
J Biol Chem 278 43736-43 (2003)
PMID: 12917404

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161854 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Immunogenic protein MPT70 Chain: A
Molecule details ›
Chain: A
Length: 163 amino acids
Theoretical weight: 16.31 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WNF5 (Residues: 31-193; Coverage: 100%)
Gene names: MTCY274.06, Rv2875, mpt70
Sequence domains: Fasciclin domain
Structure domains: FAS1 domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics with simmulated annealing
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Recent advances in our knowledge of Mycobacterium bovis: a feeling for the organism.
Hewinson et al. (2006)
6 more

6 mentions without citation

Focus on molecules: Transforming growth factor beta induced protein (TGFBIp).
Runager et al. (2008)
5 more