› 1o5h

X-ray diffraction
2.8Å resolution

Function and Biology Details

Reaction catalysed: 
5-formimidoyltetrahydrofolate = 5,10-methenyltetrahydrofolate + NH(3)
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194826 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cyclodeaminase/cyclohydrolase domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 214 amino acids
Theoretical weight: 24.82 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9X1P6 (Residues: 1-202; Coverage: 100%)
Gene name: TM_1560
Sequence domains: Formiminotransferase-cyclodeaminase
Structure domains: Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 26 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-1
Spacegroup: P212121
Unit cell:
a: 56.704Å b: 71.875Å c: 119.245Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.203 0.199 0.278
Expression system: Escherichia coli

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Citations

1 review citation

Microbial biochemistry, physiology, and biotechnology of hyperthermophilic Thermotoga species.
Conners et al. (2006)