› 1obw

X-ray diffraction
1.9Å resolution

Function and Biology Details

Reaction catalysed: 
Diphosphate + H(2)O = 2 phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-141571 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Inorganic pyrophosphatase Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 175 amino acids
Theoretical weight: 19.59 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A7A9 (Residues: 2-176; Coverage: 99%)
Gene names: JW4185, b4226, ppa
Sequence domains: Inorganic pyrophosphatase
Structure domains: Inorganic pyrophosphatase

Ligands and Environments

1 bound ligand:
Ligand MG 7 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P3221
Unit cell:
a: 110.3Å b: 110.3Å c: 78.2Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.176 0.176 0.22
Expression system: Escherichia coli

Quick links

Citations

22 citation in other articles

Mg(2+) modulates voltage-dependent activation in ether-à-go-go potassium channels by binding between transmembrane segments S2 and S3.
Silverman et al. (2000)
21 more

1 mention without citation

Structure of the Mycobacterium tuberculosis soluble inorganic pyrophosphatase Rv3628 at pH 7.0.
Benini et al. (2011)